Microscopically, the tumor was composed of a diffuse growth of vacuolated cells without cellular atypia or mitotic figures. Open in a separate window. This fibroma is hypointense on both axial T1-weighted b and T2-weighted images c.
Calcifications and keloid-like sclerosis are common. The nuclei in Krukenberg tumors usually have no atypia and occasionally have mild or moderate atypia. All ovarian neoplasms and non-neoplastic lesions composed entirely or focally of spindle cells are in the differential diagnosis of ovarian fibroma.
This group of tumors are rare constituting less than 1. Bjorkholm E, Silfversward C. Signet-ring stromal tumor of the ovary: an immunohistochemical and ultrastructural study with a review of the literature. The fascicular arrangement of smooth muscle fibers can morphologically resemble a fibroma.
These tumors are characterized by sarcomatoid growth pattern with focal pattern of conventional SLCTs.
Fibrosarcoma of ovary. Sometimes, the nuclei are eccentrically located giving signet ring like appearance [ 48 ]. Intraluminal polypoid projections lined by epithelial cells. Often, the chemo used is the same type used to treat germ cell tumors PEB: cisplatin, etoposide, and bleomycin.
The borders are infiltrative and vascular invasion is a common finding Fig. Microscopically, steroid cell tumors often exhibit a diffuse pattern with minimal to absent stroma in most cases. Despite the fact that these lesions are diffuse, they sometimes form masses up to 8 cm in size.
Namespaces Article Talk. The solid tumor portions characteristically exhibit avid contrast uptake. Tumors that induce hyperandrogenicity may present with virilization signs e. Clin Radiol. Categories : Gynaecological cancer Male genital neoplasia Ovarian cancer. Fibromas are almost always endocrine-inert tumors composed of spindle stromal cells that produce a collagenous stroma 5 , 7 , 8.